Shirley, NY – Creative Biogene is always dedicated to advancing innovative life science solutions that drive progress and impact, contributing to script the future of life sciences – transforming bold scientific possibilities into realities that heal and sustain the world. Recently, Creative Biogene is excited to announce the launch of its innovative Cas9 protein production services, which aim to support both research and industrial applications in gene editing.
As a leading provider of gene editing technology and partners, Creative Biogene offers one-stop solution of Cas protein including a broad portfolio of off-the-shelf products and customized services, with cGMP expertise and global IND track records, to provide researchers an integrated CRISPR workflow solution, accelerate clinical entry and commercialization.
The demand for high-quality Cas9 protein is increasing as more researchers and companies recognize its transformative potential in both basic science and applied biotechnology. We offer a complete set of Cas9 products from DNA clone to purified protein and specific antibody. All of them are created based on wild type Streptococcus pyogenes Cas9 protein. – Marcia Brady, the marketing director at Creative Biogene
Creative Biogene has developed advanced production methods for this important protein derived from Escherichia coli, Streptococcus pyogenes, and other microbial systems. These methods allow for efficient and scalable production, ensuring that scientists have access to the tools required for their research.
Creative Biogene offers GMP-grade Cas9 nuclease produced in accordance with Good Manufacturing Practice (GMP) guidelines; the manufacturing process encompasses aseptic production, document traceability, and rigorous testing. No animal- or human-derived components are used in the production of this product. The Cas9 protein solution has been verified as sterile and demonstrates excellent tolerability in mammalian cells when electroporated as a ribonucleoprotein (RNP) complex with single-guide RNA (sgRNA) for knockout experiments, or with a donor repair template for knock-in experiments.
Creative Biogene also provides custom Cas protein service delivers RUO to cGMP nucleases with industry leading speed, scalable manufacturing capacity, comprehensive assay development capability and IND regulatory support to accelerate therapeutic development. Creative Biogene emphasizes the importance of Good Manufacturing Practice (GMP) compliance in their processes. “At Creative Biogene, we follow stringent guidelines, which encompass aseptic manufacturing and traceable documentation. Our Cas9 proteins are rigorously tested to guarantee they are sterile and compatible for various applications,” explained Brady.
Creative Biogene’s facilities are equipped with a range of liquid and solid fermentation tanks supported by comprehensive monitoring systems. This ensures that all parameters are finely tuned to maximize efficiency and output during the fermentation process.
“Our commitment to innovation and quality positions us as a preferred partner for organizations aiming to leverage CRISPR technology in their research and development endeavors,” Brady added. She also claimed, “we offer a complete suite of gene expression and fermentation services tailored to meet the unique needs of the biotechnology sector.”
About Creative Biogene
Creative Biogene is dedicated to providing cutting-edge solutions in the field of biotechnology, specializing in gene expression services, fermentation solutions, and more. With a commitment to quality and innovation, Creative Biogene aims to be the premier source for genomic & proteomic tools to accelerate scientific breakthroughs and novel diagnostics, providing efficient, innovative, and comprehensive solutions for life science researchers, one target at a time.
