BENEO’s galenIQ™ 721 filler-binder optimizes the production of fizzy tablets and powders

2 mins read

Mannheim (Germany), To improve the taste and stability of effervescent
tablets and powders, BENEO presents galenIQ™ 721. This filler-binder enables
pharmaceutical and nutraceutical manufacturers to target consumers that have difficulty
swallowing standard tablets. As a non-hygroscopic, water-soluble and directly compressible
excipient, galenIQ™ 721 also provides high content uniformity and production efficiency for
effervescent applications.

Effervescent dosage forms offer distinct advantages compared with traditional tablets. For
instance, many patients have problems swallowing tablets. Effervescent powders and tablets
offer a more convenient way to deliver medicines or dietary supplements. They dissolve upon
contact with water to release carbon dioxide and create a drink. In addition, they can be used
to formulate pharmaceuticals that are difficult to digest, that cause stomach or esophageal
irritation or that rely on a rapid onset of action, such as analgesics.

However, manufacturing effervescent dosage forms is often challenging. To produce highly
stable tablets, a non-hygroscopic, direct compression filler-binder such as galenIQ™ 721 is
needed. It ensures high content uniformity and facilitates production. BENEO’s excipient has a
sugar-like taste profile, a pleasant mouthfeel and can enhance the palatability of effervescent
formulations. Furthermore it is non-cariogenic and therefore is both sweet and tooth-friendly.

Dr Maj-Britt Cepok, Head of Business Development, Pharma, BENEO, comments: “Fizzy tablets
are ideally suited to administer a wide range of light-, oxygen- and other sensitive active
ingredients and those that require a large dose. In addition, effervescent preparations are more

appealing to consumers than traditional dosage forms. galenIQ™ 721 helps manufacturers to
tap into this market and enhance their development programs.”

About galenIQ™
BENEO is part of the Südzucker Group and a member of the International Pharmaceutical Excipients
Council (IPEC). The company produces galenIQ™ (Isomalt Ph. Eur., BP, USP-NF, JP), a multifunctional
range of water-soluble filler-binders according to cGMP conditions for pharmaceutical excipients.
galenIQ™ is available in a wide variety of median particle sizes, morphologies and solubilities and
therefore is readily used in solid and liquid dosage forms such as tablets, sachets, effervescents,
lozenges and syrups. It is physically and chemically stable, non-hygroscopic and enhances the
palatability of the final form.
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