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Pharmacotherapeutics

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pharmacotherapeutics

How Are Drugs Used Clinically in Patients? The study of the therapeutic uses and effects of drugs in patients is called pharmacotherapeutics. The focus of pharmacotherapy is the patient, not the drug or the disease. [wp_ad_camp_1] Drugs do not behave in the same way in all individuals, and patientto-patient variability in drug response is very common. Therapeutic variability may be caused by differences in patient body size and composition, age, disease, environmental factors, and genetic influences. It may also be attributable…

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Antisense Drugs

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How antisense drugs work

Definition, Designing Technology and Mechanism  Antisense drugs are drugs that seek to block DNA transcription or RNA translation in order to moderate many disease processes. Antisense drugs consist of nucleotides linked

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Alternative Medicine

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Often called ‘‘complementary and alternative medicine,’’ this group of medical practices has also been termed ‘‘unconventional,’’ ‘‘unorthodox,’’ ‘‘unproven,’’ and even ‘‘quackery.’’ Because these terms have significant negative connotations, terms such as ‘‘alternative medicine’’ are preferred. Alternative medicine is not one form of medicine, but rather a diverse group of health practices that are outside of what is considered usual or conventional by the medical establishment. Alternative medicine spans the range of practices, from home remedies to manufactured products, from patient self-treatment to care by a skilled practitioner, from efficacious to potentially…

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Adverse Drug Reactions

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Adverse drug reactions (ADRs) are types of adverse drug events (ADEs). ADEs include ADRs, medication errors, and other drug-related problems. ADEs are the negative

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Drug Tolerance

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Tolerance may be defined as either (1) the loss of effect over time to the same dose of a drug or (2) the need for more of a drug over time to get the same effect. Tolerance, at first, appears counterintuitive because addition of more of an activating ligand lessens the elicited response. [wp_ad_camp_5] Recall, however, that receptor number and receptor sensitivity are dynamic and that signaling can adjust based on the conditions of ligand availability. Given that drugs often times act…

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